A promising new test for Johne’s Disease in dairy cattle has the potential to ramp up eradication efforts, offering fewer missed positives.
The new test has been developed at the Institute for Global Food Security and School of Biological Sciences at Queen’s University Belfast.
It's said to be faster and more sensitive at detecting the infectious agent (MAP) of Johne’s Disease in veterinary specimens and is showing greater detection capability than the milk-ELISA test that is currently used.
Crucially, it detects live infectious agent, not just antibodies against MAP as are detected by milk-ELISA.
In a recent study, the new test was able to detect more infected animals by milk testing than milk-ELISA, so could potentially facilitate control of Johne’s faster. As well as bovine milk, the new test can also be applied to faeces and blood from livestock.
The test was developed by Prof. Irene Grant and her post-doctoral researcher Dr. Antonio Foddai at IGFS and their research was published in the open-access journal Applied Microbiology and Biotechnology.
They hope to now move to the applied stage of the science with further development and validation of their test for MAP infection at farm level.
Prof. Grant said: “As farmers will know, Johne’s Disease is an endemic animal health issue worldwide, particularly in dairy herds. It is certainly present in Northern Ireland dairy herds but the true prevalence of Johne’s in the local context is not accurately known.
I hope our test will offer more accurate, rapid and quantitative results, and therefore help farmers and vets make more informed decisions about the infection status of animals in order to control the disease more effectively within herds.
“I also hope it will generate more accurate data on the prevalence of Johne’s Disease within Northern Ireland and therefore build a better picture of this animal-health problem.”
The new test for Johne’s disease was developed as part of an Agri-Food Quest Competence Centre project, and was a collaboration between IGFS; AgriSearch; Biorex Food Diagnostics; and Dale Farm.