Researchers from Queen’s University Belfast have questioned the World Health Organisation’s blanket classification of processed meat as carcinogenic, arguing that not all processed meats carry the same level of cancer risk.

Dr. Brian Green, Dr. William Crowe and Prof. Chris Elliott OBE, all from the Institute for Global Food Security (IGFS) at Queen’s, reviewed existing peer-reviewed literature on the relationship between processed meat and the development of bowel, colon and rectal cancers.

The results of their meta-analysis have been published in the high-impact journal Nutrients.

The three initially reviewed all recent English-language studies into the consumption of processed meat and cancer risk and found the results inconclusive – only around half the studies evidenced a link with colorectal cancer (CRC).

But when the researchers isolated research which only tested the consumption of processed meat containing sodium nitrite – a preservative used to extend shelf life and enhance colour – evidence of a link with CRC jumped from half to just under two-thirds – 65%.

The team's findings explain the appearance of contradictory claims in the media in recent years.

“When we looked at nitrite-containing processed meat in isolation – which is the first time this has been done in a comprehensive study – the results were much clearer,” explained research fellow Dr. William Crowe. “Almost two-thirds of studies found a link with cancer.”

Different processing methods

The WHO classified all processed meat as a carcinogen in 2015 – including bacon, sausages and ham as well as continental European products like prosciutto and salami.

Not all processed meat, however, contains nitrites.

British and Irish sausages, for example, are not processed with nitrites, even though many of the Continental and US sausage equivalents – like frankfurters, pepperoni and chorizo – are.

Some newer types of bacon and ham, processed without nitrites, are also appearing on the market.

In its 2015 statement, the WHO did not distinguish between processed meats containing nitrites and those without. Based on the results of their meta-study, the IGFS researchers now believe there is a need to define the health risk of both types of processed meat – separately.

Co-author Prof. Chris Elliott OBE, who carried out the UK Government’s inquiry into food safety after the horsemeat scandal, said this latest research brought more clarity to what has been a confusing area for the food industry and the public.

He said: “Because there have been conflicting claims in the scientific community and the media about which types of meat may be carcinogenic, this study couldn’t have come at a better time. It brings much-needed rigour and clarity and points the way for further research in this area.”

Livestock and Meat Commission chief executive Ian Stevenson was among those to welcome the findings.

He said: "As an industry, the beef and lamb sectors rely heavily on scientific evidence to support policy development and business decision making.

All too often our industry and its products are subject to unfair pressures as a result of misrepresentation of science or unfounded scaremongering by ill-informed commentators. Red Meat continues to form an essential part of a healthy balanced diet as indicated by the Department of Health’s current guidance.

Study lead author, Dr. Brian Green added: “The current Department of Health guidance advises the public to consume no more than 70g of red or processed meat per day.

“That remains the guidance, but we hope that future research investigating the link between diet and CRC will consider each type of meat individually rather than grouping them together. Our findings clearly show that not all processed meats, for example, carry the same level of risk.

“There is more research to be done before we can definitively prove causality regarding processed meat and cancer – there are so many variables when it comes to people’s diets.

"But based on our study, which we believe provides the most thorough review of the evidence on nitrites to date, what we can confidently say is that a strong link exists between nitrite-containing processed meat, such as frankfurters, and CRC.”

The IGFS team intends following up its evidence review with a pre-clinical study probing the effects of nitrite-containing meat on CRC.

The meta-analysis was funded by Invest NI through the Agri-Food Quest Competence Centre, which links scientific researchers with industry partners for research projects. The industry partners in this study were: Karro, Cranswick and Finnebrogue Artisan.